Li, XiaokangSoler, MariaSzydzik, CrispinKhoshmanesh, KhashayarSchmidt, JulienYesilkoy, FilizBelushkin, AlexanderCoukos, GeorgeMitchell, ArnanAltug, Hatice2019-11-272019-11-272019-11-272019-01-0110.1109/PRIME.2019.8787840https://infoscience.epfl.ch/handle/20.500.14299/163413WOS:000494800400029An innovative nanoplasmonic biosensor was presented for real-time label-free monitoring of cytokine secretion at single-cell resolution. This biosensor is integrated with a uniquely designed microfluidic device that provides a microchamber for cell incubation and fluid regulation for stable live cell monitoring. Different spatiotemporal profiles of interleukin-2 secretion were observed from single lymphoma cells. This novel configuration of label-free biosensor is promising for single-cell related studies.label-freenanoplasmonicssingle-cell analysismicrofluidicsextraordinary optical-transmissionfabricationpdmstext::conference output::conference proceedings::conference paper