Zanoli, SilvioAnsaloni, GiovanniTeijeiro, TomasAtienza, David2023-08-282023-08-282023-08-282023-10-0110.1016/j.cmpb.2023.107712https://infoscience.epfl.ch/handle/20.500.14299/200128WOS:001044498800001Background and Objective: Event-based analog-to-digital converters allow for sparse bio-signal acquisition, enabling local sub-Nyquist sampling frequency. However, aggressive event selection can cause the loss of important bio-markers, not recoverable with standard interpolation techniques. In this work, we leverage the self-similarity of the electrocardiogram (ECG) signal to recover missing features in event-based sam-pled ECG signals, dynamically selecting patient-representative templates together with a novel dynamic time warping algorithm to infer the morphology of event-based sampled heartbeats.Methods: We acquire a set of uniformly sampled heartbeats and use a graph-based clustering algorithm to define representative templates for the patient. Then, for each event-based sampled heartbeat, we select the morphologically nearest template, and we then reconstruct the heartbeat with piece-wise linear de-formations of the selected template, according to a novel dynamic time warping algorithm that matches events to template segments.Results: Synthetic tests on a standard normal sinus rhythm dataset, composed of approximately 1.8 million normal heartbeats, show a big leap in performance with respect to standard resampling techniques. In particular (when compared to classic linear resampling), we show an improvement in P-wave detection of up to 10 times, an improvement in T-wave detection of up to three times, and a 30% improvement in the dynamic time warping morphological distance.Conclusion: In this work, we have developed an event-based processing pipeline that leverages signal self -similarity to reconstruct event-based sampled ECG signals. Synthetic tests show clear advantages over classical resampling techniques.& COPY; 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license ( http://creativecommons.org/licenses/by/4.0/ )Computer Science, Interdisciplinary ApplicationsComputer Science, Theory & MethodsEngineering, BiomedicalMedical InformaticsComputer ScienceEngineeringnon-uniform samplingbiosignal monitoringevent-basedecgmorphology reconstructiondynamic time warpingecg morphologytext::journal::journal article::research article