Perillat, Valentin JeanDel Grosso, EricaBerton, CesareRicci, FrancescoPezzato, Cristian2023-03-132023-03-132023-03-132023-02-0210.1039/d2cc06525hhttps://infoscience.epfl.ch/handle/20.500.14299/195794WOS:000924131800001Control over synthetic DNA-based nanodevices can be achieved with a variety of physical and chemical stimuli. Actuation with light, however, is as advantageous as difficult to implement without modifying DNA strands with photo-switchable groups. Herein, we show that DNA nanodevices can be controlled using visible light in photo-switchable aqueous buffer solutions in a reversible and highly programmable fashion. The strategy presented here is non-invasive and allows the remote control with visible light of complex operations of DNA-based nanodevices such as the reversible release/loading of cargo molecules.Chemistry, MultidisciplinaryChemistrymolecular machinenanostructuresstatetext::journal::journal article::research article