000098619 001__ 98619
000098619 005__ 20190316233909.0
000098619 0247_ $$2doi$$a10.1006/jtbi.1996.0160
000098619 037__ $$aARTICLE
000098619 245__ $$aMCA has more to say
000098619 269__ $$a1996
000098619 260__ $$c1996
000098619 336__ $$aJournal Articles
000098619 500__ $$a9-0 FIELD Section Title:Biochemical Methods
000098619 500__ $$aInst. Biotechnol.,Zurich,Switz. FIELD URL:
000098619 500__ $$awritten in English.
000098619 520__ $$aA review with many refs. The recent development of two math. frameworks for the anal. and design of metabolic systems is reviewed here with many refs. Both frameworks employ a (log)linear kinetic metabolic model that is constructed making direct, explicit use of the individual enzyme kinetic parameters which are a foundation of Metabolic Control Anal. (MCA) information. The first framework allows the description of the dynamic responses of metabolic systems subject to fluctuations in their parameters. The second framework considers the problem of optimizing the regulatory structure of metabolic networks. Both frameworks are powerful in enabling greater insights into metab. based on MCA quantities. [on SciFinder (R)]
000098619 6531_ $$aMetabolic Control Analysis review
000098619 700__ $$0240657$$g174688$$aHatzimanikatis, Vassily
000098619 700__ $$aBailey, James E.
000098619 773__ $$j182$$tJournal of Theoretical Biology$$k3$$q233-242
000098619 8564_ $$uhttps://infoscience.epfl.ch/record/98619/files/vh-1996-5.pdf$$zn/a$$s255068
000098619 909C0 $$xU11422$$0252131$$pLCSB
000098619 909CO $$ooai:infoscience.tind.io:98619$$qGLOBAL_SET$$pSB$$particle
000098619 937__ $$aLCSB-ARTICLE-1996-003
000098619 970__ $$a0000000047/LCSB
000098619 973__ $$rREVIEWED$$sPUBLISHED$$aOTHER
000098619 980__ $$aARTICLE