The Spike Response Model: A Framework to Predict Neuronal Spike Trains
We propose a simple method to map a generic threshold model, namely the Spike Response Model, to artificial data of neuronal activity using a minimal amount of a priori information. Here, data are generated by a detailed mathematical model of neuronal activity. The model neuron is driven with in-vivo-like current injected, and we test to which extent it is possible to predict the spike train of the detailed neuron model from that of the Spike Response Model. In particular, we look at the number of spikes correctly predicted within a biologically relevant time window. We find that the Spike Response Model achieves prediction of up to $80%$ of the spikes with correct timing ($\pm2$ms). Other characteristics of activity, such as mean rate and coefficient of variation of spike trains, are predicted in the correct range as well.
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Record created on 2006-12-12, modified on 2016-08-08