To be or not to be a pro-T?

Recent studies have begun to unravel some of the molecular pathways that appear to control the processes of T cell determination in the earliest thymocyte precursors. In addition, the analyses of mouse mutants with an entirely alymphoid thymus have shed light on the developmental relationship of pro-T cells and thymic dendritic cells, revealing that development of thymocytes and thymic dendritic cells can be dissociated.


Published in:
Curr Opin Immunol, 12, 2, 159-65
Year:
2000
Keywords:
Note:
Unite des Cytokines et Developpement Lymphoide, Institut Pasteur, Paris, F-75724, France. disanto@pasteur.fr
0952-7915 (Print)
Journal Article
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 Record created 2006-12-05, last modified 2018-03-17

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