Highly enantio- and diastereoselective inverse electron demand hetero-Diels-Alder reaction
A highly enantioselective and diastereoselective inverse electron demand hetero-Diels-Alder reaction between a variety of alpha,beta-unsatd. aldehydes and Et vinyl ether is described. The reaction is catalyzed by a chiral tridentate chromium(III) Schiff base complex, which is obtained by a concise and highly efficient protocol in two steps from com. materials. The resulting cycloadducts are isolated in good yields and are useful synthetic intermediates. [on SciFinder (R)]
FIELD Section Title:
Department of Chemistry and Chemical Biology,Harvard University,Cambridge,MA,USA. FIELD URL:
written in English.
Record created on 2006-11-22, modified on 2016-08-08