Abstract

A highly enantioselective and diastereoselective inverse electron demand hetero-Diels-Alder reaction between a variety of alpha,beta-unsatd. aldehydes and Et vinyl ether is described. The reaction is catalyzed by a chiral tridentate chromium(III) Schiff base complex, which is obtained by a concise and highly efficient protocol in two steps from com. materials. The resulting cycloadducts are isolated in good yields and are useful synthetic intermediates. [on SciFinder (R)]

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