The findings of two recent studies suggest a novel mechanism for nuclear envelope breakdown in which cytoplasmic dynein anchored on the outside of the nucleus generates tension, thus triggering tearing of the nuclear envelope.
Title
Nuclear envelope: torn apart at mitosis
Published in
Current Biology
Volume
12
Issue
7
Pages
R242-R244
Date
2002
ISSN
0960-9822
Note
ISREC (Swiss Institute for Experimental Cancer Research), 155, ch. des Boveresses, CH-1066, Epalinges/Lausanne, Switzerland. Pierre.Gönczy@isrec.unil.ch
Journal Article
Review
Record creation date
2006-08-24