A General and Simple Removal of Allyloxycarbonyl Protecting Group by Palladium-Mediated Reactions Using Nitrogen and Sulfur Nucleophiles
1993
Abstract
Smooth removal of the Allyloxycarbonyl (Alloc) moiety from allylic esters, carbamates and carbonates is carried out by Pd (O) catalyzed allyl transfer to diethylamine and thio derivatives as the accepting nucleophiles. The method has been successfully used for selective deprotection of secondary amines and base sensitive substrates.
Details
Title
A General and Simple Removal of Allyloxycarbonyl Protecting Group by Palladium-Mediated Reactions Using Nitrogen and Sulfur Nucleophiles
Author(s)
Genêt, Jean Pierre ; Blart, Erol ; Savignac, Monique ; Lemaire-Audoire, Sandrine ; Bernard, Jean-Marie
Published in
Synlett
Issue
9
Pages
680-682
Date
1993
ISSN
0936-5214
Keywords
Laboratories
LGSA
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > SB Archives > LGSA - Laboratory of Glycochemistry and Asymmetric Synthesis
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Record creation date
2006-06-16