000086007 001__ 86007
000086007 005__ 20181203020421.0
000086007 037__ $$aARTICLE
000086007 245__ $$aDerivatives of (2R,3R,4S)-2-Aminomethylpyrrolidine-3,4-diol are Selective alpha-Mannosidase Inhibitors
000086007 269__ $$a2001
000086007 260__ $$c2001
000086007 336__ $$aJournal Articles
000086007 520__ $$aA collection of (2R,3R,4S)-3,4-dihydroxypyrrolidin-2-yl derivatives have been tested for their inhibitory activities toward 25 glycosidases. Competitive (K-i=7.4 VM) and selective inhibition of alpha -mannosidase from jack bean has been found for (2R,3R,4S)-2-[(benzylamino)methyl]pyrrolidine-3,4-diol and other derivatives.
000086007 6531_ $$a3 deoxy derivatives
000086007 6531_ $$amannostatin-a
000086007 6531_ $$aglycosidase inhibitors
000086007 6531_ $$abiological-activities
000086007 6531_ $$aadvanced malignancies
000086007 6531_ $$aprocessing inhibitor
000086007 6531_ $$aclass-i
000086007 6531_ $$aswainsonine
000086007 6531_ $$athioglycoside
000086007 6531_ $$adisaccharides
000086007 700__ $$0241594$$aPopowycz, Florence$$g148384
000086007 700__ $$0241092$$aGerber-Lemaire, Sandrine$$g148571
000086007 700__ $$0241591$$aDemange, Raynald$$g148252
000086007 700__ $$0241353$$aRodriguez-Garcia, Eliaizar$$g148386
000086007 700__ $$0241593$$aCarmona Asenjo, Ana Teresa$$g159352
000086007 700__ $$aRobina, Inmaculada
000086007 700__ $$0240222$$aVogel, Pierre$$g123681
000086007 773__ $$j11$$q2489-2493$$tBioorganic and Medicinal Chemistry Letters
000086007 909C0 $$0252076$$pLGSA$$xU10111
000086007 909CO $$ooai:infoscience.tind.io:86007$$pSB$$particle
000086007 937__ $$aLGSA-ARTICLE-2006-007
000086007 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000086007 980__ $$aARTICLE