Infoscience

Journal article

Solvent-controlled additions of organotitanium reagents to olefinic double bonds

Under carefully chosen working conditions (solvent, temp.), methyltitanium reagents smoothly convert homoallyl alcs. having a terminal double-bond into (E)-3-penten-1-ols, whereas nonterminal 3-alken-1-ols afford 4-methyl-branched derivs. with configurational inversion of the chain. Stereoselectivities were >99%. [on SciFinder (R)]

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