Alkyl/halogen substitution in carbenes (carbenoids): a route to new cyclopropane derivatives
1971
Abstract
7-Halo-7-methylnorcaranes (I) and 7,7-dimethylnorcarane (II) are formed via replacement of halogen by Me during the reaction of cyclohexene (III) with carbenes (carbenoids) and MeLi. Thus, III is treated with CHClF2 or CCl2F2 and MeLi to give a mixt. of 7-chloro-7-fluoronorcarane (IV), I, and II. 1,1-Difluoro-2,2-dimethylcyclopropanes (V) are obtained from Me2C:CHMe and Me2C:CH(CH2)2CH(OEt)2. [on SciFinder (R)]
Details
Title
Alkyl/halogen substitution in carbenes (carbenoids): a route to new cyclopropane derivatives
Author(s)
Schlosser, Manfred ; Le, Van Chau
Published in
Angewandte Chemie, International Edition
Volume
10
Issue
2
Pages
138-9
Date
1971
Keywords
Note
CAN 74:141049 24 Alicyclic Compounds Org.-Chem. Inst.,Univ. Heidelberg,Heidelberg,Fed. Rep. Ger. Journal 0570-0833 written in English. 1460-19-1P; 26650-62-4P; 31707-69-4P; 31754-77-5P; 31754-78-6P; 31754-79-7P; 31754-80-0P; 31772-74-4P; 31772-75-5P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of); 917-54-4 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with methane halo derivs. and olefins); 75-45-6; 75-71-8 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with methyllithium and olefins)
Laboratories
LSCO
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > SB Archives > LSCO - Laboratory of Organic Synthesis and Catalysis
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Peer-reviewed publications
Work outside EPFL
Journal Articles
Published
Record creation date
2006-03-03