Triple helix binding of oligodeoxyribonucleotides containing 8-oxo-2'-deoxyadenosine
1993
Abstract
Formation of a triple helix between an oligodeoxyribonucleotide contg. 8-oxo-2'-deoxyadenosine and a DNA duplex target was studied as a function of pH. Above pH 7.4, the triple helix with the 8-oxo-2'-deoxyadenosine was more stable than the complex with an analogous oligodeoxyribonucleotide contg. deoxycytidine instead of 8-oxo-2'-deoxyadenosine.
Details
Title
Triple helix binding of oligodeoxyribonucleotides containing 8-oxo-2'-deoxyadenosine
Author(s)
Davison, Edwin C. ; Johnsson, Kai
Published in
Nucleosides & Nucleotides
Volume
12
Issue
2
Pages
237-43
Date
1993
Laboratories
LIP
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LIP - Laboratory of Protein Engineering
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date
2006-02-27