Protein release from PEG hydrogels that are similar to ideal Flory-Rehner networks

A new crosslinking scheme for producing polyethylene glycol hydrogels is described, involving a conjugate addn. reaction between PEG-multiacrylate and PEG-dithiol. Albumin was released from the gels with zero-order kinetics over four days. The gels are amenable to math. description, and the swelling of the gels is modeled by the Flory-Rehner and Peppas-Merrill equations. [on SciFinder (R)]


Published in:
Proceedings - 28th International Symposium on Controlled Release of Bioactive Materials and 4th Consumer & Diversified Products Conference, San Diego, CA, United States, June 23-27, 2001, 2, 987-988
Year:
2001
Laboratories:




 Record created 2006-02-27, last modified 2018-07-07


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