Encapsulation of the protein drug hGH in degradable polyethylene glycol-based hydrogel microspheres was demonstrated to result in burst-free release appropriate for a once-per-week prepn. of the drug. Small needle sizes, lack of burst, and lack of local inflammation appear to be advantageous. [on SciFinder (R)]
Title
A novel drug delivery system for recombinant human growth hormone with photopolymerized hydrogels
Published in
Proceedings - 28th International Symposium on Controlled Release of Bioactive Materials and 4th Consumer & Diversified Products Conference, San Diego, CA, United States, June 23-27, 2001
Volume
2
Pages
985-986
Date
2001
Record creation date
2006-02-27