Membrane-spanning bent helix modeling receptor protein channel function
Boheim, Guenther; Helbig, Inge; Meder, Sabine; Vogel, Horst; Nilsson, Lennart; Rigler, Rudolf; Franz, Brigitte; Jung, Guenther
1990

Abstract

Dansyl-(Ala-Aib-Ala-Aib-Ala)3-Pro-Ala-Aib-Ala-Aib-Ala-Trp-OMe [(I), where Aib is a-aminoisobutryate] is a bent a-helical peptide which displays ion channel activity characteristic of the nicotinic acetylcholine receptor. The membrane organization, side-chain and backbone motions, and voltage dependence of the I ion channel are discussed. [on SciFinder (R)]

Details

Title Membrane-spanning bent helix modeling receptor protein channel function
Author(s) Boheim, Guenther ; Helbig, Inge ; Meder, Sabine ; Vogel, Horst ; Nilsson, Lennart ; Rigler, Rudolf ; Franz, Brigitte ; Jung, Guenther
Published in Peptides : chemistry, structure and biology
Pages 658-60
Conference Eleventh American Peptide Symposium, La Jolla, California, U.S.A., July 9-14, 1989
Date 1990
Laboratories LCPPM
Record Appears in Scientific production and competences > SB - School of Basic Sciences > SB Archives > LCPPM - Laboratory of Physical Chemistry of Polymers and Membranes
Peer-reviewed publications
Conference Papers
Work produced at EPFL
Published
Record creation date 2006-02-27

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