Synthetic helical polypeptide models the acetylcholine receptor channel function
Jung, Gunther; Franz, Brigitte; Boheim, Gunther; Helbig, Inge; Meder, Sabine; Nilsson, Lennart; Rigler, Rudolf; Vogel, Horst
1989

Abstract

A review with 11 refs. on a fluorescent Aib-contg. peptide model for the acetylcholine receptor ion channel. This peptide induces single-channel conductance in planar lipid bilayers exhibiting one single open conductance state and weakly voltage-dependent kinetics. The peptides fluorescent dansyl group can be used to correlate motions of the peptide helix with channel opening and closing. [on SciFinder (R)]

Details

Title Synthetic helical polypeptide models the acetylcholine receptor channel function
Author(s) Jung, Gunther ; Franz, Brigitte ; Boheim, Gunther ; Helbig, Inge ; Meder, Sabine ; Nilsson, Lennart ; Rigler, Rudolf ; Vogel, Horst
Published in Proceedings of the 3rd Akabori Conference: German-Japanese Symposium on Peptide Chemistry
Pages 140-145
Date 1989
Laboratories LCPPM
Record Appears in Scientific production and competences > SB - School of Basic Sciences > SB Archives > LCPPM - Laboratory of Physical Chemistry of Polymers and Membranes
Peer-reviewed publications
Conference Papers
Work produced at EPFL
Published
Record creation date 2006-02-27