Conference paper

Synthetic helical polypeptide models the acetylcholine receptor channel function

A review with 11 refs. on a fluorescent Aib-contg. peptide model for the acetylcholine receptor ion channel. This peptide induces single-channel conductance in planar lipid bilayers exhibiting one single open conductance state and weakly voltage-dependent kinetics. The peptides fluorescent dansyl group can be used to correlate motions of the peptide helix with channel opening and closing. [on SciFinder (R)]


    • LCPPM-CONF-1989-001

    Record created on 2006-02-27, modified on 2016-08-08


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