Ceramic hydroxyapatite: a new tool for separation and analysis of IgA monoclonal antibodies
Lullau, E.; Marison, I. W.; Von Stockar, U.
1997

Abstract

A novel downstream process is reported for preparative scale prodn. of dimeric IgA, a protein with potential pharmaceutical applications. Time-consuming size exclusion chromatog. was replaced by ceramic hydroxyapatite chromatog. (CHT). A clear baseline sepn. of the dimeric IgA from the polymeric forms using a step-gradient-step protein elution program is described. Application of this method for IgA anal. during prodn. is suggested. [on SciFinder (R)]

Details

Title Ceramic hydroxyapatite: a new tool for separation and analysis of IgA monoclonal antibodies
Author(s) Lullau, E. ; Marison, I. W. ; Von Stockar, U.
Published in Animal Cell Technology: From Vaccines to Genetic Medicine, [Proceedings of the Meeting of the ESACT], 14th, Vilamoura, Port., May 1996
Pages 265-269
Date 1997
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Laboratories LGCB
Record Appears in Scientific production and competences > SB - School of Basic Sciences > SB Archives > LGCB - Laboratory of Chemical and Biological Engineering
Peer-reviewed publications
Conference Papers
Work produced at EPFL
Published
Record creation date 2006-02-27