Highly selective excitation in biomolecular NMR by frequency-switched single-transition cross-polarization

A new method for selective excitation in biomol. NMR uses two-fold single-transition cross-polarization between protons and nitrogen-15 or carbon-13 nuclei. Switching the frequencies between the forward and backward transfer steps allows one to select a multiplet pattern that is assocd. with a single pair of spins in a medium-size protein. The efficiency of the transfer benefits from so-called TROSY line-narrowing effects which arise from interference between relaxation mechanisms. [on SciFinder (R)]


Published in:
Journal of the American Chemical Society, 124, 10, 2076-2077
Year:
2002
Laboratories:




 Record created 2006-02-22, last modified 2018-03-17


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