Selective hydrolysis of anti-1,3-diol-acetonides for the differentiation of 1,3-anti and 1,3-syn diols

A mild and general method for the selective cleavage of anti-1,3-acetonides has been developed for the differentiation of 1,3-anti and 1,3-syn diols in long chain polyolic fragments. The diluted acidic conditions applied to these systems are compatible with other common protecting groups such as silyl ethers and benzyloxymethyl ethers.


Published in:
Tetrahedron Letters, 47, 5, 671-674
Year:
2006
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 Record created 2006-02-16, last modified 2018-03-17

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