Protein de novo design: Macromolecules with tailormade properties

In the absence of a detailed knowledge of the folding mechanism of natural proteins, the general design of polypeptide sequences with a high propensity to fold into a predetermined three dimensional structure still appears to be out of reach. The concept of Template Assembled Synthetic Proteins (TASP) represents a means by which one call nonetheless construct macromolecules with native-like structural features, with the result that systems with tailormade structural and functional properties are non becoming attainable.


Published in:
Macromol. Symp., 101, 397-404
Year:
1996
ISSN:
1022-1360
Laboratories:




 Record created 2006-02-09, last modified 2018-01-27


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