Infoscience

Journal article

A CONVENIENT SYNTHESIS OF CYCLIC-PEPTIDES AS REGIOSELECTIVELY ADDRESSABLE FUNCTIONALIZED TEMPLATES (RAFT)

Cyclic decapeptides containing up to four orthogonally protected lysine residues have been efficiently prepared by a combined solid phase and solution strategy. These cyclic peptides represent new Regioselectively Addressable Functionalized Templates (RAFT), which are suitable for use in protein de novo design according to the TASP concept.

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