Infoscience

Conference paper

Chromatographic characterization of template assembled synthetic proteins (TASP) and other large peptides using narrow-bore IEC, RPHPLC, CZE and MS analysis

Reversed-phase HPLC can not be relied on as the only chromatog. step for the purifn. and anal. of synthetic peptides larger than 30 to 40 residues; therefore their purity should be documented by more than one anal. technique. Narrow-bore ion-exclusion chromatog. and capillary zone electrophoresis complement reversed-phase HPLC for the detn. of the purity of synthetic peptides. Similarly, mass spectroscopy is used for the identification of all synthetic peptides. [on SciFinder (R)]

    Reference

    • LCBP-CONF-1991-001

    Record created on 2006-02-09, modified on 2016-08-08

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