One-pot, three-component synthesis of open-chain, polyfunctional sulfones

Silyl enol ethers of esters, ketones, as well as allylstannane and allylsilanes react with sulfur dioxide activated with t-BuMe2SiOSO2CF3 to give silyl sulfinates that can be reacted in the same pot with a variety of electrophiles generating the corresponding polyfunctional sulfones. The silyl sulfinate intermediates are formed via ene-reactions following probably concerted mechanisms.


Published in:
Synthesis-Stuttgart, 2, 225-231
Year:
2002
ISSN:
0039-7881
Keywords:
Note:
Ecole Polytech Fed Lausanne, Inst Chim Mol & Biol, Lausanne, Switzerland.
Other identifiers:
Laboratories:




 Record created 2005-11-09, last modified 2018-03-17


Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)