Abstract
The Diels-Alder adduct of 2,4-dimethylfuran and 1-cyanovinyl acetate was converted with high stereoselectivity into 1,3,5-trimefilylcyclohexen-4,6-diol derivatives that can be cleaved into protected polypropionate fragments.
Details
Title
Polypropionate Fragments with 4 Contiguous Chiral Centers from Acetone
Author(s)
Bialecki, M. ; Vogel, P.
Published in
Tetrahedron Letters
Volume
35
Issue
29
Pages
5213-5216
Date
1994
ISSN
0040-4039
Keywords
1; 5-dimethyl-7-oxabicyclo[2.2.1]hept-5-en-2-yl; s(n)2' ring opening; (3rs; 4sr; 5sr; 6sr)-4; 6-dibenzyloxy-1; 3; 5-trimethylcyclohexene; (2rs; 3sr; 4rs; 5rs)-3; 5-dibenzyloxy-2; 4-dimethyl-6-oxoheptonal; Stereocontrolled synthesis; rutamycin-b; sulfones; rapamycin; subunit; stereochemistry; hydrogenolysis; construction; antibiotics
Note
Univ lausanne,chim sect,ch-1005 lausanne,switzerland.
Laboratories
LGSA
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > SB Archives > LGSA - Laboratory of Glycochemistry and Asymmetric Synthesis
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date
2005-11-09