Total, Asymmetric-Synthesis of (1r)-1-C-(6'-Amino-7'h-Purin-8'-Yl)-1,4-Anhydro-3-Azido-2,3-Dideoxy-D-Er Ythro-Pentitol
1992
Abstract
The "naked sugar" (+)-(1R,2R,4R)-2-cyano-7-oxabicyclo[2.2.1]hept-5-en-2-exo-yl acetate ((+)-3) was converted in ten synthetic steps into the new C-nucleoside (1R)-1-C-(6'-amino-7'H-purin-8'-yl)-1,4-anhydro-3-azido-2,3-dideoxy-D-er ythro-pentitol ((+)-2) in 19% overall yield.
Details
Title
Total, Asymmetric-Synthesis of (1r)-1-C-(6'-Amino-7'h-Purin-8'-Yl)-1,4-Anhydro-3-Azido-2,3-Dideoxy-D-Er Ythro-Pentitol
Author(s)
Jeanneret, V. ; Gasparini, F. ; Pechy, P. ; Vogel, P.
Published in
Tetrahedron
Volume
48
Issue
48
Pages
10637-10644
Date
1992
ISSN
0040-4020
Keywords
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LPI - Laboratory of Photonics and Interfaces
Scientific production and competences > SB - School of Basic Sciences > SB Archives > LGSA - Laboratory of Glycochemistry and Asymmetric Synthesis
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Scientific production and competences > SB - School of Basic Sciences > SB Archives > LGSA - Laboratory of Glycochemistry and Asymmetric Synthesis
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date
2005-11-09