Substituent Effects on the Regioselectivity of One-Carbon Ring Expansions of 7-Oxabicyclo[2.2.1]Heptan-2-One Derivatives with Diazomethane

Reactions of CH2N2 with 5-exo,6-exo-isopropylidenedioxy-7-oxabicyclo[2.2.1]heptan-2-one and 3-substituted derivatives have been studied. The regioselectivity of the one-carbon ring enlargement process depends on the nature of the substituent at C(3) and on its relative configuration.


Published in:
Tetrahedron Letters, 32, 13, 1637-1640
Year:
1991
ISSN:
0040-4039
Keywords:
Laboratories:




 Record created 2005-11-09, last modified 2018-03-17


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