Impedance spectroscopy flow cytometry: Model validation

A number of microfabricated flow cytometry devices have been proposed based on electrical(1,2) or optical(3) detection techniques. On chip marker-free differentiation of cells using impedance spectroscopy was demonstrated between leukocyte sub-populations and on erythrocytes+ghosts mixtures.(4) The detection part of the chip includes 4 microelectrodes patterned on the top and bottom walls of a rectangular microchannel which define two detection volumes (Figure 1). Although preliminary results showed the potential of the impedance measurement using specific frequencies, a systemic approach is required to determine an optimal set of discrimination frequencies for cell sorting.


Published in:
MICRO TOTAL ANALYSIS SYSTEMS 2004, VOL 1, 296, 58-60
Presented at:
8th International Conference on Miniiaturized Systems for Chemistry and Life Sciences, Malmo, SWEDEN, SEP 26-30, 2004
Year:
2005
Laboratories:




 Record created 2005-09-13, last modified 2018-07-07


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