Impedance spectroscopy flow cytometry: Parameters for label-free cell differentiation

This work presents label-free separation of cells in an on-chip flow cytometer based on impedance spectroscopy. The amplitude, opacity, and phase information can be used for discrimination depending on the cell types. Red blood cells, ghosts, and fixed cells are differentiated based on differences in their membrane and cytoplasm dielectric properties. Among other applications, detecting changes in cell conductivity and membrane capacitance will allow the indentification of early-stage apoptosis or cancer.


Published in:
MICRO TOTAL ANALYSIS SYSTEMS 2004, VOL 1, 296, 55-57
Presented at:
8th International Conference on Miniiaturized Systems for Chemistry and Life Sciences, Malmo, SWEDEN, SEP 26-30, 2004
Year:
2005
Laboratories:




 Record created 2005-09-13, last modified 2018-07-07


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