A microbial-derived succinylated bile acid to safeguard liver health
2024
Abstract
In this issue of Cell, Nie and co-authors report that the microbe-derived bile acid (BA) 3-succinylated cholic acid protects against the progression of metabolic dysfunction-associated liver disease. Intriguingly, its protective mechanism does not involve traditional BA signaling pathways but is instead linked to the proliferation of the commensal microbe Akkermansia muciniphila.
Details
Title
A microbial-derived succinylated bile acid to safeguard liver health
Published in
Cell
Volume
187
Issue
11
Pages
2687-2689
Date
2024-05-23
Publisher
Cambridge, Cell Press
ISSN
0092-8674
1097-4172
1097-4172
Other identifier(s)
View record in Web of Science
Laboratories
LISP
Record Appears in
Scientific production and competences > SV - School of Life Sciences > IBI-SV - Interfaculty Institute of Bioengineering > LISP - Laboratory of Integrative Systems Physiology
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Grant
Ecole Polytechnique Federale de Lausanne, Switzerland
Swiss National Science Foundation: SNSF 310030_189178
EFSD/Boehringer Ingelheim European Research Program on "Multi-System Challenges in Diabetes"
Swiss National Science Foundation: SNSF 310030_189178
EFSD/Boehringer Ingelheim European Research Program on "Multi-System Challenges in Diabetes"
Record creation date
2024-07-03