A Cobalt Nanocatalyst for the Hydrogenation and Oxidative Dehydrogenation of N-heterocycles
Catalytic hydrogenation and oxidative dehydrogenation of N-heterocycles to produce tetrahydroquinoline and quinoline derivatives are important reactions of particular importance in the agrochemical and pharmaceutical industries. Herein, we report earth-abundant cobalt nanoparticles supported on hydroxyapatite (HAP) as an inexpensive and efficient catalyst for the hydrogenation and reverse oxidative dehydrogenation of N-heterocycles. The optimal nanocatalyst exhibits excellent activity in both reactions for a wide range of substrates including (iso)quinolines, acridine, benzo[h]quinoline, quinoxaline and indole. Reactions proceed under relatively mild conditions without requiring any additives.|Non-noble catalyst for hydrogenation and oxidative dehydrogenation of N-heterocycles process: Pyrolysis of Co-PZ-TPA supported on hydroxyapatite resulting in an active and reusable core-shell nanocatalyst with high activity in hydrogenation and its reversible oxidative dehydrogenation of N-heterocycles.image
WOS:001096392100001
2023-11-06
16
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Funder | Grant Number |
Deutsche Forschungsgemeinschaft (DFG) | 447724917 |
State of Mecklenburg-Vorpommern | |
European Union | 101006744 |