The present invention concerns a biological material pooling device for biological or biomolecule purification comprising a receptacle including a first orifice comprising ordefining a rectangular opening, the receptacle being configured to receive at least one liquid through the first orifice, a second orifice located opposite the first orifice; and at least one side wall extending between the first orifice and the second orifice. The at least one side wall extends between the first orifice and the second orifice to define a tapered cavity or a cavity of decreasing cross-sectional area between the first orifice and the second orifice to guide and remove the at least one liquid out of the biological material pooling device.