Sulfated and sulfonated dendritic polyglycerols and use thereof as broad-spectrum virucidal agents
The invention relates to dendritic polyglycerol (dPG) compounds with alkyl-sulfonate/ sulfate functional groups that irreversibly inhibit viral infection (virucidal effect) through multivalent interaction in nanomolar concentration range. While the compounds of the invention show virus inhibition in the nanomolar range they show no in-vitro toxicity in the same range of concentration.
71894697
Alternative title(s) : (fr) Polyglycérols dendritiques sulfatés et sulfonés et leur utilisation en tant qu'agents virucides à large spectre
TTO:6.1514.2
| Patent number | Country code | Kind code | Date issued |
EP4188984 | EP | A1 | 2023-06-07 |
EP4188985 | EP | A1 | 2023-06-07 |
US2023165891 | US | A1 | 2023-06-01 |
WO2022023335 | WO | A1 | 2022-02-03 |
WO2022023435 | WO | A1 | 2022-02-03 |