Continuous hydrothermal flow synthesis (CHFS) of Ni-Fe layered double hydroxide (LDH) leads to waterborne dispersions of 2D nanoplatelets in the range of 10-50 nm in lateral size. Conversion of the as-synthesized LDH nanoplatelet dispersion into inkjet printing inks results in high precision patterning and complete substrate coverage with low LDH loadings in the range of mu g cm(-2). The Ni-Fe LDHs' anisotropy induces a preferential inplane alignment to a glassy carbon substrate producing low-porosity films. Thin Ni-Fe LDH films in the submicrometer range exhibit superior electrocatalytic activity for the oxygen evolution reaction (OER), with an overpotential of 270 mV at 10 mA cm(-2) and a Tafel slope of 32 mV dec(-1). The particle alignment creates a compact film and induces a loading-independent electrochemical performance of the Ni-Fe LDH electrodes for loadings above 50 mu g cm(-2). The combination of CHFS and inkjet printing represents a promising hyphenation of large-scale synthesis and electrode production.