000028316 001__ 28316
000028316 005__ 20180127183224.0
000028316 037__ $$aCONF
000028316 245__ $$aOptimization of a Semi-Batch Reaction System under Safety Constraints
000028316 269__ $$a1999
000028316 260__ $$c1999
000028316 336__ $$aConference Papers
000028316 520__ $$aOPTIMIZATION OF A SEMI-BATCH REACTION SYSTEM UNDER SAFETY CONSTRAINTS O. Ubrich+, B. Srinivasan*, F. Stoessel+, D. Bonvin* *  Novartis Services AG, CH-4002 Basel, Switzerland Institut d’ utomatique, Ecole Polytechnique Fédérale de Lausanne A CH-1015, Lausanne, Switzerland * Fax: +41 21 693 2574 and e-mail: dominique.bonvin@epfl.ch  +  An important objective in the chemical industry is to find the operating conditions that maximize profit while ensuring safe operation. The safety considerations arise from the exothermic nature of most industrial chemical reactions. For normal operation, the system must be able to remove the heat produced. But at the same time, the system must be capable of withstanding a cooling failure. These goals are best achieved in a semi-batch reactor, since the contents of the reactor can be controlled by the external feed. In this paper, the maximization of the yield of a second-order reaction by manipulating the inlet flow rate is investigated. Two modes of operation are considered: (a) the isoperibolic mode, where the temperature of the cooling fluid is kept constant, and (b) the isothermal mode, where the temperature of the reaction mass is kept constant by adjusting the temperature of the cooling fluid. Constraints on (i) the amount of heat produced, and (ii) the temperature under cooling failure are imposed for safety considerations. The optimal solution is discontinuous and is first obtained numerically. Analytical expressions for the evolution of the input between the discontinuities and the switching times are obtained. Using the analytical characterization of the optimal solution, an efficient feedback implementation strategy is proposed and tested in simulation.
000028316 700__ $$aUbrich, O.
000028316 700__ $$0240471$$aSrinivasan, B.$$g106464
000028316 700__ $$aStoessel, F.
000028316 700__ $$0240449$$aBonvin, D.$$g104596
000028316 773__ $$tECC'99
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000028316 909C0 $$0252053$$pLA
000028316 909CO $$ooai:infoscience.tind.io:28316$$pSTI$$pconf
000028316 917Z8 $$x104596
000028316 937__ $$aLA-CONF-1999-016
000028316 970__ $$a67/LA
000028316 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000028316 980__ $$aCONF