Ultraviolet Photodissociation of Peptides: New Insight on the Mobile Proton Model

In this work, we study the mechanism of peptide photodissociation by ultraviolet irradiation at 193 nm wavelength and discuss the role of ionization proton in this process. We found that substituting the ionization proton for the alkali metal cations (sodium) in the peptide ions results in significant changes of the photodissociation spectra. The experimental data obtained in this work revealed that the photodissociation process can be described using the mobile proton model introduced earlier for peptide collision dissociation. The results can be used in proteomics research for optimization of mass spectrometer's parameters to increase the efficiency of peptide dissociation and in developing sequence-specific models for peptide fragmentation prediction.


Published in:
Journal Of Experimental And Theoretical Physics, 130, 4, 626-632
Year:
Apr 01 2020
Publisher:
Moscow, PLEIADES PUBLISHING INC
ISSN:
1063-7761
1090-6509
Keywords:
Laboratories:




 Record created 2020-06-06, last modified 2020-10-27


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