000261986 001__ 261986
000261986 005__ 20181217115213.0
000261986 022__ $$a1047-3211
000261986 022__ $$a1460-2199
000261986 02470 $$2isi$$a000443545600025
000261986 0247_ $$2doi$$a10.1093/cercor/bhy156
000261986 037__ $$aARTICLE
000261986 245__ $$aAudio-Tactile and Peripersonal Space Processing Around the Trunk in Human Parietal and Temporal Cortex: An Intracranial EEG Study
000261986 260__ $$aCary$$bOXFORD UNIV PRESS INC$$c2018
000261986 269__ $$a2018-09-01
000261986 336__ $$aJournal Articles
000261986 520__ $$aInteractions with the environment happen within one's peripersonal space (PPS)-the space surrounding the body. Studies in monkeys and humans have highlighted a multisensory distributed cortical network representing the PPS. However, knowledge about the temporal dynamics of PPS processing around the trunk is lacking. Here, we recorded intracranial electroencephalography (iEEG) in humans while administering tactile stimulation (T), approaching auditory stimuli (A), and the 2 combined (AT). To map PPS, tactile stimulation was delivered when the sound was far, intermediate, or close to the body. The 19% of the electrodes showed AT multisensory integration. Among those, 30% showed a PPS effect, a modulation of the response as a function of the distance between the sound and body. AT multisensory integration and PPS effects had similar spatiotemporal characteristics, with an early response (similar to 50 ms) in the insular cortex, and later responses (similar to 200 ms) in precentral and postcentral gyri. Superior temporal cortex showed a different response pattern with AT multisensory integration at similar to 100 ms without a PPS effect. These results, represent the first iEEG delineation of PPS processing in humans and show that PPS and multisensory integration happen at similar neural sites and time periods, suggesting that PPS representation is based on a spatial modulation of multisensory integration.
000261986 650__ $$aNeurosciences
000261986 650__ $$aNeurosciences & Neurology
000261986 6531_ $$ainsula
000261986 6531_ $$aintracranial electroencephalography
000261986 6531_ $$amultisensory
000261986 6531_ $$aperipersonal space
000261986 6531_ $$aposterior parietal cortex
000261986 6531_ $$abodily self-consciousness
000261986 6531_ $$aventral intraparietal area
000261986 6531_ $$aauditory association cortex
000261986 6531_ $$amultisensory integration
000261986 6531_ $$abody ownership
000261986 6531_ $$ahuman brain
000261986 6531_ $$aaudiotactile interaction
000261986 6531_ $$aposterior parietal
000261986 6531_ $$alooming signals
000261986 6531_ $$apremotor cortex
000261986 700__ $$0248067$$aBernasconi, Fosco
000261986 700__ $$aNoel, Jean-Paul
000261986 700__ $$aPark, Hyeong Dong
000261986 700__ $$0247996$$aFaivre, Nathan
000261986 700__ $$aSeeck, Margitta
000261986 700__ $$aSpinelli, Laurent
000261986 700__ $$aSchaller, Karl
000261986 700__ $$0240593$$aBlanke, Olaf
000261986 700__ $$0246654$$aSerino, Andrea
000261986 773__ $$j28$$k9$$q3385-3397$$tCerebral Cortex
000261986 909CO $$ooai:infoscience.epfl.ch:261986$$particle
000261986 961__ $$afantin.reichler@epfl.ch
000261986 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000261986 980__ $$aARTICLE
000261986 980__ $$aWoS
000261986 981__ $$aoverwrite
000261986 999C0 $$0252325$$mmarco.solca@epfl.ch$$pLNCO$$xU11025$$zBlumer, Eliane
000261986 999C0 $$0252449$$meliane.blumer@epfl.ch$$pBMI$$xU10454$$zBlumer, Eliane