Modeling CLiMP-63 spatio-temporal distribution and its interplay with Post-translational modification

Post-translational modifications may affect a protein’s localization, half-life or structural conformation. Palmitoylation is the only re- versible lipid modification known to date. It involves the attachment of a fatty acid (palmitoyl) to a protein. Here, radiolabeling experiments are used to calibrate a mathematical model describing CLiMP-63 localization, palmitoylation and dimerization.


Advisor(s):
Hatzimanikatis, Vassily
van der Goot, Gisou
Presented at:
5th Conference on Constraint-Based Reconstruction and Analysis, Seattle, United States of America, October 14-16, 2018
Year:
Sep 01 2018
Laboratories:




 Record created 2018-11-12, last modified 2019-04-15


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