000255534 001__ 255534
000255534 005__ 20190317000957.0
000255534 0247_ $$a10.1016/j.cell.2018.03.034$$2doi
000255534 02470 $$2DOI$$a10.1016/j.cell.2018.03.034
000255534 02470 $$2PMID$$a29625051
000255534 037__ $$aARTICLE
000255534 245__ $$aMachine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation
000255534 260__ $$c2018-04-05
000255534 269__ $$a2018-04-05
000255534 336__ $$aJournal Articles
000255534 520__ $$aCancer progression involves the gradual loss of a differentiated phenotype and acquisition of progenitor and stem-cell-like features. Here, we provide novel stemness indices for assessing the degree of oncogenic dedifferentiation. We used an innovative one-class logistic regression (OCLR) machine-learning algorithm to extract transcriptomic and epigenetic feature sets derived from non-transformed pluripotent stem cells and their differentiated progeny. Using OCLR, we were able to identify previously undiscovered biological mechanisms associated with the dedifferentiated oncogenic state. Analyses of the tumor microenvironment revealed unanticipated correlation of cancer stemness with immune checkpoint expression and infiltrating immune cells. We found that the dedifferentiated oncogenic phenotype was generally most prominent in metastatic tumors. Application of our stemness indices to single-cell data revealed patterns of intra-tumor molecular heterogeneity. Finally, the indices allowed for the identification of novel targets and possible targeted therapies aimed at tumor differentiation.
000255534 542__ $$fCC BY-NC-ND
000255534 700__ $$aMalta, Tathiane M.
000255534 700__ $$aSokolov, Artem
000255534 700__ $$aGentles, Andrew J.
000255534 700__ $$aBurzykowski, Tomasz
000255534 700__ $$aPoisson, Laila
000255534 700__ $$aWeinstein, John N.
000255534 700__ $$aKamińska, Bożena
000255534 700__ $$aHuelsken, Joerg
000255534 700__ $$aOmberg, Larsson
000255534 700__ $$aGevaert, Olivier
000255534 700__ $$aColaprico, Antonio
000255534 700__ $$aCzerwińska, Patrycja
000255534 700__ $$aMazurek, Sylwia
000255534 700__ $$aMishra, Lopa
000255534 700__ $$aHeyn, Holger
000255534 700__ $$aKrasnitz, Alex
000255534 700__ $$aGodwin, Andrew K.
000255534 700__ $$aLazar, Alexander J.
000255534 700__ $$aStuart, Joshua M.
000255534 700__ $$aHoadley, Katherine A.
000255534 700__ $$aLaird, Peter W.
000255534 700__ $$aNoushmehr, Houtan
000255534 700__ $$aWiznerowicz, Maciej
000255534 700__ $$aCaesar-Johnson, Samantha J.
000255534 700__ $$aDemchok, John A.
000255534 700__ $$aFelau, Ina
000255534 700__ $$aKasapi, Melpomeni
000255534 700__ $$aFerguson, Martin L.
000255534 700__ $$aHutter, Carolyn M.
000255534 700__ $$aSofia, Heidi J.
000255534 700__ $$aTarnuzzer, Roy
000255534 700__ $$aWang, Zhining
000255534 700__ $$aYang, Liming
000255534 700__ $$aZenklusen, Jean C.
000255534 700__ $$aZhang, Jiashan (Julia)
000255534 700__ $$aChudamani, Sudha
000255534 700__ $$aLiu, Jia
000255534 700__ $$aLolla, Laxmi
000255534 700__ $$aNaresh, Rashi
000255534 700__ $$aPihl, Todd
000255534 700__ $$aSun, Qiang
000255534 700__ $$aWan, Yunhu
000255534 700__ $$aWu, Ye
000255534 700__ $$aCho, Juok
000255534 700__ $$aDeFreitas, Timothy
000255534 700__ $$aFrazer, Scott
000255534 700__ $$aGehlenborg, Nils
000255534 700__ $$aGetz, Gad
000255534 700__ $$aHeiman, David I.
000255534 700__ $$aKim, Jaegil
000255534 700__ $$aLawrence, Michael S.
000255534 700__ $$aLin, Pei
000255534 700__ $$aMeier, Sam
000255534 700__ $$aNoble, Michael S.
000255534 700__ $$aSaksena, Gordon
000255534 700__ $$aVoet, Doug
000255534 700__ $$aZhang, Hailei
000255534 700__ $$aBernard, Brady
000255534 700__ $$aChambwe, Nyasha
000255534 700__ $$aDhankani, Varsha
000255534 700__ $$aKnijnenburg, Theo
000255534 700__ $$aKramer, Roger
000255534 700__ $$aLeinonen, Kalle
000255534 700__ $$aLiu, Yuexin
000255534 700__ $$aMiller, Michael
000255534 700__ $$aReynolds, Sheila
000255534 700__ $$aShmulevich, Ilya
000255534 700__ $$aThorsson, Vesteinn
000255534 700__ $$aZhang, Wei
000255534 700__ $$aAkbani, Rehan
000255534 700__ $$aBroom, Bradley M.
000255534 700__ $$aHegde, Apurva M.
000255534 700__ $$aJu, Zhenlin
000255534 700__ $$aKanchi, Rupa S.
000255534 700__ $$aKorkut, Anil
000255534 700__ $$aLi, Jun
000255534 700__ $$aLiang, Han
000255534 700__ $$aLing, Shiyun
000255534 700__ $$aLiu, Wenbin
000255534 700__ $$aLu, Yiling
000255534 700__ $$aMills, Gordon B.
000255534 700__ $$aNg, Kwok-Shing
000255534 700__ $$aRao, Arvind
000255534 700__ $$aRyan, Michael
000255534 700__ $$aWang, Jing
000255534 700__ $$aZhang, Jiexin
000255534 700__ $$aAbeshouse, Adam
000255534 700__ $$aArmenia, Joshua
000255534 700__ $$aChakravarty, Debyani
000255534 700__ $$aChatila, Walid K.
000255534 700__ $$ade Bruijn, Ino
000255534 700__ $$aGao, Jianjiong
000255534 700__ $$aGross, Benjamin E.
000255534 700__ $$aHeins, Zachary J.
000255534 700__ $$aKundra, Ritika
000255534 700__ $$aLa, Konnor
000255534 700__ $$aLadanyi, Marc
000255534 700__ $$aLuna, Augustin
000255534 700__ $$aNissan, Moriah G.
000255534 700__ $$aOchoa, Angelica
000255534 700__ $$aPhillips, Sarah M.
000255534 700__ $$aReznik, Ed
000255534 700__ $$aSanchez-Vega, Francisco
000255534 700__ $$aSander, Chris
000255534 700__ $$aSchultz, Nikolaus
000255534 700__ $$aSheridan, Robert
000255534 700__ $$aSumer, S. Onur
000255534 700__ $$aSun, Yichao
000255534 700__ $$aTaylor, Barry S.
000255534 700__ $$aWang, Jioajiao
000255534 700__ $$aZhang, Hongxin
000255534 700__ $$aAnur, Pavana
000255534 700__ $$aPeto, Myron
000255534 700__ $$aSpellman, Paul
000255534 700__ $$aBenz, Christopher
000255534 700__ $$aWong, Christopher K.
000255534 700__ $$aYau, Christina
000255534 700__ $$aHayes, D. Neil
000255534 700__ $$aParker, Joel S.
000255534 700__ $$aWilkerson, Matthew D.
000255534 700__ $$aAlly, Adrian
000255534 700__ $$aBalasundaram, Miruna
000255534 700__ $$aBowlby, Reanne
000255534 700__ $$aBrooks, Denise
000255534 700__ $$aCarlsen, Rebecca
000255534 700__ $$aChuah, Eric
000255534 700__ $$aDhalla, Noreen
000255534 700__ $$aHolt, Robert
000255534 700__ $$aJones, Steven J.M.
000255534 700__ $$aKasaian, Katayoon
000255534 700__ $$aLee, Darlene
000255534 700__ $$aMa, Yussanne
000255534 700__ $$aMarra, Marco A.
000255534 700__ $$aMayo, Michael
000255534 700__ $$aMoore, Richard A.
000255534 700__ $$aMungall, Andrew J.
000255534 700__ $$aMungall, Karen
000255534 700__ $$aRobertson, A. Gordon
000255534 700__ $$aSadeghi, Sara
000255534 700__ $$aSchein, Jacqueline E.
000255534 700__ $$aSipahimalani, Payal
000255534 700__ $$aTam, Angela
000255534 700__ $$aThiessen, Nina
000255534 700__ $$aTse, Kane
000255534 700__ $$aWong, Tina
000255534 700__ $$aBerger, Ashton C.
000255534 700__ $$aBeroukhim, Rameen
000255534 700__ $$aCherniack, Andrew D.
000255534 700__ $$aCibulskis, Carrie
000255534 700__ $$aGabriel, Stacey B.
000255534 700__ $$aGao, Galen F.
000255534 700__ $$aHa, Gavin
000255534 700__ $$aMeyerson, Matthew
000255534 700__ $$aSchumacher, Steven E.
000255534 700__ $$aShih, Juliann
000255534 700__ $$aKucherlapati, Melanie H.
000255534 700__ $$aKucherlapati, Raju S.
000255534 700__ $$aBaylin, Stephen
000255534 700__ $$aCope, Leslie
000255534 700__ $$aDanilova, Ludmila
000255534 700__ $$aBootwalla, Moiz S.
000255534 700__ $$aLai, Phillip H.
000255534 700__ $$aMaglinte, Dennis T.
000255534 700__ $$aVan Den Berg, David J.
000255534 700__ $$aWeisenberger, Daniel J.
000255534 700__ $$aAuman, J. Todd
000255534 700__ $$aBalu, Saianand
000255534 700__ $$aBodenheimer, Tom
000255534 700__ $$aFan, Cheng
000255534 700__ $$aHoyle, Alan P.
000255534 700__ $$aJefferys, Stuart R.
000255534 700__ $$aJones, Corbin D.
000255534 700__ $$aMeng, Shaowu
000255534 700__ $$aMieczkowski, Piotr A.
000255534 700__ $$aMose, Lisle E.
000255534 700__ $$aPerou, Amy H.
000255534 700__ $$aPerou, Charles M.
000255534 700__ $$aRoach, Jeffrey
000255534 700__ $$aShi, Yan
000255534 700__ $$aSimons, Janae V.
000255534 700__ $$aSkelly, Tara
000255534 700__ $$aSoloway, Matthew G.
000255534 700__ $$aTan, Donghui
000255534 700__ $$aVeluvolu, Umadevi
000255534 700__ $$aFan, Huihui
000255534 700__ $$aHinoue, Toshinori
000255534 700__ $$aShen, Hui
000255534 700__ $$aZhou, Wanding
000255534 700__ $$aBellair, Michelle
000255534 700__ $$aChang, Kyle
000255534 700__ $$aCovington, Kyle
000255534 700__ $$aCreighton, Chad J.
000255534 700__ $$aDinh, Huyen
000255534 700__ $$aDoddapaneni, HarshaVardhan
000255534 700__ $$aDonehower, Lawrence A.
000255534 700__ $$aDrummond, Jennifer
000255534 700__ $$aGibbs, Richard A.
000255534 700__ $$aGlenn, Robert
000255534 700__ $$aHale, Walker
000255534 700__ $$aHan, Yi
000255534 700__ $$aHu, Jianhong
000255534 700__ $$aKorchina, Viktoriya
000255534 700__ $$aLee, Sandra
000255534 700__ $$aLewis, Lora
000255534 700__ $$aLi, Wei
000255534 700__ $$aLiu, Xiuping
000255534 700__ $$aMorgan, Margaret
000255534 700__ $$aMorton, Donna
000255534 700__ $$aMuzny, Donna
000255534 700__ $$aSantibanez, Jireh
000255534 700__ $$aSheth, Margi
000255534 700__ $$aShinbrot, Eve
000255534 700__ $$aWang, Linghua
000255534 700__ $$aWang, Min
000255534 700__ $$aWheeler, David A.
000255534 700__ $$aXi, Liu
000255534 700__ $$aZhao, Fengmei
000255534 700__ $$aHess, Julian
000255534 700__ $$aAppelbaum, Elizabeth L.
000255534 700__ $$aBailey, Matthew
000255534 700__ $$aCordes, Matthew G.
000255534 700__ $$aDing, Li
000255534 700__ $$aFronick, Catrina C.
000255534 700__ $$aFulton, Lucinda A.
000255534 700__ $$aFulton, Robert S.
000255534 700__ $$aKandoth, Cyriac
000255534 700__ $$aMardis, Elaine R.
000255534 700__ $$aMcLellan, Michael D.
000255534 700__ $$aMiller, Christopher A.
000255534 700__ $$aSchmidt, Heather K.
000255534 700__ $$aWilson, Richard K.
000255534 700__ $$aCrain, Daniel
000255534 700__ $$aCurley, Erin
000255534 700__ $$aGardner, Johanna
000255534 700__ $$aLau, Kevin
000255534 700__ $$aMallery, David
000255534 700__ $$aMorris, Scott
000255534 700__ $$aPaulauskis, Joseph
000255534 700__ $$aPenny, Robert
000255534 700__ $$aShelton, Candace
000255534 700__ $$aShelton, Troy
000255534 700__ $$aSherman, Mark
000255534 700__ $$aThompson, Eric
000255534 700__ $$aYena, Peggy
000255534 700__ $$aBowen, Jay
000255534 700__ $$aGastier-Foster, Julie M.
000255534 700__ $$aGerken, Mark
000255534 700__ $$aLeraas, Kristen M.
000255534 700__ $$aLichtenberg, Tara M.
000255534 700__ $$aRamirez, Nilsa C.
000255534 700__ $$aWise, Lisa
000255534 700__ $$aZmuda, Erik
000255534 700__ $$aCorcoran, Niall
000255534 700__ $$aCostello, Tony
000255534 700__ $$aHovens, Christopher
000255534 700__ $$aCarvalho, Andre L.
000255534 700__ $$ade Carvalho, Ana C.
000255534 700__ $$aFregnani, José H.
000255534 700__ $$aLongatto-Filho, Adhemar
000255534 700__ $$aReis, Rui M.
000255534 700__ $$aScapulatempo-Neto, Cristovam
000255534 700__ $$aSilveira, Henrique C.S.
000255534 700__ $$aVidal, Daniel O.
000255534 700__ $$aBurnette, Andrew
000255534 700__ $$aEschbacher, Jennifer
000255534 700__ $$aHermes, Beth
000255534 700__ $$aNoss, Ardene
000255534 700__ $$aSingh, Rosy
000255534 700__ $$aAnderson, Matthew L.
000255534 700__ $$aCastro, Patricia D.
000255534 700__ $$aIttmann, Michael
000255534 700__ $$aHuntsman, David
000255534 700__ $$aKohl, Bernard
000255534 700__ $$aLe, Xuan
000255534 700__ $$aThorp, Richard
000255534 700__ $$aAndry, Chris
000255534 700__ $$aDuffy, Elizabeth R.
000255534 700__ $$aLyadov, Vladimir
000255534 700__ $$aPaklina, Oxana
000255534 700__ $$aSetdikova, Galiya
000255534 700__ $$aShabunin, Alexey
000255534 700__ $$aTavobilov, Mikhail
000255534 700__ $$aMcPherson, Christopher
000255534 700__ $$aWarnick, Ronald
000255534 700__ $$aBerkowitz, Ross
000255534 700__ $$aCramer, Daniel
000255534 700__ $$aFeltmate, Colleen
000255534 700__ $$aHorowitz, Neil
000255534 700__ $$aKibel, Adam
000255534 700__ $$aMuto, Michael
000255534 700__ $$aRaut, Chandrajit P.
000255534 700__ $$aMalykh, Andrei
000255534 700__ $$aBarnholtz-Sloan, Jill S.
000255534 700__ $$aBarrett, Wendi
000255534 700__ $$aDevine, Karen
000255534 700__ $$aFulop, Jordonna
000255534 700__ $$aOstrom, Quinn T.
000255534 700__ $$aShimmel, Kristen
000255534 700__ $$aWolinsky, Yingli
000255534 700__ $$aSloan, Andrew E.
000255534 700__ $$aDe Rose, Agostino
000255534 700__ $$aGiuliante, Felice
000255534 700__ $$aGoodman, Marc
000255534 700__ $$aKarlan, Beth Y.
000255534 700__ $$aHagedorn, Curt H.
000255534 700__ $$aEckman, John
000255534 700__ $$aHarr, Jodi
000255534 700__ $$aMyers, Jerome
000255534 700__ $$aTucker, Kelinda
000255534 700__ $$aZach, Leigh Anne
000255534 700__ $$aDeyarmin, Brenda
000255534 700__ $$aHu, Hai
000255534 700__ $$aKvecher, Leonid
000255534 700__ $$aLarson, Caroline
000255534 700__ $$aMural, Richard J.
000255534 700__ $$aSomiari, Stella
000255534 700__ $$aVicha, Ales
000255534 700__ $$aZelinka, Tomas
000255534 700__ $$aBennett, Joseph
000255534 700__ $$aIacocca, Mary
000255534 700__ $$aRabeno, Brenda
000255534 700__ $$aSwanson, Patricia
000255534 700__ $$aLatour, Mathieu
000255534 700__ $$aLacombe, Louis
000255534 700__ $$aTêtu, Bernard
000255534 700__ $$aBergeron, Alain
000255534 700__ $$aMcGraw, Mary
000255534 700__ $$aStaugaitis, Susan M.
000255534 700__ $$aChabot, John
000255534 700__ $$aHibshoosh, Hanina
000255534 700__ $$aSepulveda, Antonia
000255534 700__ $$aSu, Tao
000255534 700__ $$aWang, Timothy
000255534 700__ $$aPotapova, Olga
000255534 700__ $$aVoronina, Olga
000255534 700__ $$aDesjardins, Laurence
000255534 700__ $$aMariani, Odette
000255534 700__ $$aRoman-Roman, Sergio
000255534 700__ $$aSastre, Xavier
000255534 700__ $$aStern, Marc-Henri
000255534 700__ $$aCheng, Feixiong
000255534 700__ $$aSignoretti, Sabina
000255534 700__ $$aBerchuck, Andrew
000255534 700__ $$aBigner, Darell
000255534 700__ $$aLipp, Eric
000255534 700__ $$aMarks, Jeffrey
000255534 700__ $$aMcCall, Shannon
000255534 700__ $$aMcLendon, Roger
000255534 700__ $$aSecord, Angeles
000255534 700__ $$aSharp, Alexis
000255534 700__ $$aBehera, Madhusmita
000255534 700__ $$aBrat, Daniel J.
000255534 700__ $$aChen, Amy
000255534 700__ $$aDelman, Keith
000255534 700__ $$aForce, Seth
000255534 700__ $$aKhuri, Fadlo
000255534 700__ $$aMagliocca, Kelly
000255534 700__ $$aMaithel, Shishir
000255534 700__ $$aOlson, Jeffrey J.
000255534 700__ $$aOwonikoko, Taofeek
000255534 700__ $$aPickens, Alan
000255534 700__ $$aRamalingam, Suresh
000255534 700__ $$aShin, Dong M.
000255534 700__ $$aSica, Gabriel
000255534 700__ $$aVan Meir, Erwin G.
000255534 700__ $$aZhang, Hongzheng
000255534 700__ $$aEijckenboom, Wil
000255534 700__ $$aGillis, Ad
000255534 700__ $$aKorpershoek, Esther
000255534 700__ $$aLooijenga, Leendert
000255534 700__ $$aOosterhuis, Wolter
000255534 700__ $$aStoop, Hans
000255534 700__ $$avan Kessel, Kim E.
000255534 700__ $$aZwarthoff, Ellen C.
000255534 700__ $$aCalatozzolo, Chiara
000255534 700__ $$aCuppini, Lucia
000255534 700__ $$aCuzzubbo, Stefania
000255534 700__ $$aDiMeco, Francesco
000255534 700__ $$aFinocchiaro, Gaetano
000255534 700__ $$aMattei, Luca
000255534 700__ $$aPerin, Alessandro
000255534 700__ $$aPollo, Bianca
000255534 700__ $$aChen, Chu
000255534 700__ $$aHouck, John
000255534 700__ $$aLohavanichbutr, Pawadee
000255534 700__ $$aHartmann, Arndt
000255534 700__ $$aStoehr, Christine
000255534 700__ $$aStoehr, Robert
000255534 700__ $$aTaubert, Helge
000255534 700__ $$aWach, Sven
000255534 700__ $$aWullich, Bernd
000255534 700__ $$aKycler, Witold
000255534 700__ $$aMurawa, Dawid
000255534 700__ $$aChung, Ki
000255534 700__ $$aEdenfield, W. Jeffrey
000255534 700__ $$aMartin, Julie
000255534 700__ $$aBaudin, Eric
000255534 700__ $$aBubley, Glenn
000255534 700__ $$aBueno, Raphael
000255534 700__ $$aDe Rienzo, Assunta
000255534 700__ $$aRichards, William G.
000255534 700__ $$aKalkanis, Steven
000255534 700__ $$aMikkelsen, Tom
000255534 700__ $$aScarpace, Lisa
000255534 700__ $$aGirard, Nicolas
000255534 700__ $$aAymerich, Marta
000255534 700__ $$aCampo, Elias
000255534 700__ $$aGiné, Eva
000255534 700__ $$aGuillermo, Armando López
000255534 700__ $$aVan Bang, Nguyen
000255534 700__ $$aHanh, Phan Thi
000255534 700__ $$aPhu, Bui Duc
000255534 700__ $$aTang, Yufang
000255534 700__ $$aColman, Howard
000255534 700__ $$aEvason, Kimberley
000255534 700__ $$aDottino, Peter R.
000255534 700__ $$aMartignetti, John A.
000255534 700__ $$aGabra, Hani
000255534 700__ $$aJuhl, Hartmut
000255534 700__ $$aAkeredolu, Teniola
000255534 700__ $$aStepa, Serghei
000255534 700__ $$aHoon, Dave
000255534 700__ $$aAhn, Keunsoo
000255534 700__ $$aKang, Koo Jeong
000255534 700__ $$aBeuschlein, Felix
000255534 700__ $$aBreggia, Anne
000255534 700__ $$aBirrer, Michael
000255534 700__ $$aBell, Debra
000255534 700__ $$aBorad, Mitesh
000255534 700__ $$aBryce, Alan H.
000255534 700__ $$aCastle, Erik
000255534 700__ $$aChandan, Vishal
000255534 700__ $$aCheville, John
000255534 700__ $$aCopland, John A.
000255534 700__ $$aFarnell, Michael
000255534 700__ $$aFlotte, Thomas
000255534 700__ $$aGiama, Nasra
000255534 700__ $$aHo, Thai
000255534 700__ $$aKendrick, Michael
000255534 700__ $$aKocher, Jean-Pierre
000255534 700__ $$aKopp, Karla
000255534 700__ $$aMoser, Catherine
000255534 700__ $$aNagorney, David
000255534 700__ $$aO’Brien, Daniel
000255534 700__ $$aO’Neill, Brian Patrick
000255534 700__ $$aPatel, Tushar
000255534 700__ $$aPetersen, Gloria
000255534 700__ $$aQue, Florencia
000255534 700__ $$aRivera, Michael
000255534 700__ $$aRoberts, Lewis
000255534 700__ $$aSmallridge, Robert
000255534 700__ $$aSmyrk, Thomas
000255534 700__ $$aStanton, Melissa
000255534 700__ $$aThompson, R. Houston
000255534 700__ $$aTorbenson, Michael
000255534 700__ $$aYang, Ju Dong
000255534 700__ $$aZhang, Lizhi
000255534 700__ $$aBrimo, Fadi
000255534 700__ $$aAjani, Jaffer A.
000255534 700__ $$aGonzalez, Ana Maria Angulo
000255534 700__ $$aBehrens, Carmen
000255534 700__ $$aBondaruk, Jolanta
000255534 700__ $$aBroaddus, Russell
000255534 700__ $$aCzerniak, Bogdan
000255534 700__ $$aEsmaeli, Bita
000255534 700__ $$aFujimoto, Junya
000255534 700__ $$aGershenwald, Jeffrey
000255534 700__ $$aGuo, Charles
000255534 700__ $$aLogothetis, Christopher
000255534 700__ $$aMeric-Bernstam, Funda
000255534 700__ $$aMoran, Cesar
000255534 700__ $$aRamondetta, Lois
000255534 700__ $$aRice, David
000255534 700__ $$aSood, Anil
000255534 700__ $$aTamboli, Pheroze
000255534 700__ $$aThompson, Timothy
000255534 700__ $$aTroncoso, Patricia
000255534 700__ $$aTsao, Anne
000255534 700__ $$aWistuba, Ignacio
000255534 700__ $$aCarter, Candace
000255534 700__ $$aHaydu, Lauren
000255534 700__ $$aHersey, Peter
000255534 700__ $$aJakrot, Valerie
000255534 700__ $$aKakavand, Hojabr
000255534 700__ $$aKefford, Richard
000255534 700__ $$aLee, Kenneth
000255534 700__ $$aLong, Georgina
000255534 700__ $$aMann, Graham
000255534 700__ $$aQuinn, Michael
000255534 700__ $$aSaw, Robyn
000255534 700__ $$aScolyer, Richard
000255534 700__ $$aShannon, Kerwin
000255534 700__ $$aSpillane, Andrew
000255534 700__ $$aStretch, Jonathan
000255534 700__ $$aSynott, Maria
000255534 700__ $$aThompson, John
000255534 700__ $$aWilmott, James
000255534 700__ $$aAl-Ahmadie, Hikmat
000255534 700__ $$aChan, Timothy A.
000255534 700__ $$aGhossein, Ronald
000255534 700__ $$aGopalan, Anuradha
000255534 700__ $$aLevine, Douglas A.
000255534 700__ $$aReuter, Victor
000255534 700__ $$aSinger, Samuel
000255534 700__ $$aSingh, Bhuvanesh
000255534 700__ $$aTien, Nguyen Viet
000255534 700__ $$aBroudy, Thomas
000255534 700__ $$aMirsaidi, Cyrus
000255534 700__ $$aNair, Praveen
000255534 700__ $$aDrwiega, Paul
000255534 700__ $$aMiller, Judy
000255534 700__ $$aSmith, Jennifer
000255534 700__ $$aZaren, Howard
000255534 700__ $$aPark, Joong-Won
000255534 700__ $$aHung, Nguyen Phi
000255534 700__ $$aKebebew, Electron
000255534 700__ $$aLinehan, W. Marston
000255534 700__ $$aMetwalli, Adam R.
000255534 700__ $$aPacak, Karel
000255534 700__ $$aPinto, Peter A.
000255534 700__ $$aSchiffman, Mark
000255534 700__ $$aSchmidt, Laura S.
000255534 700__ $$aVocke, Cathy D.
000255534 700__ $$aWentzensen, Nicolas
000255534 700__ $$aWorrell, Robert
000255534 700__ $$aYang, Hannah
000255534 700__ $$aMoncrieff, Marc
000255534 700__ $$aGoparaju, Chandra
000255534 700__ $$aMelamed, Jonathan
000255534 700__ $$aPass, Harvey
000255534 700__ $$aBotnariuc, Natalia
000255534 700__ $$aCaraman, Irina
000255534 700__ $$aCernat, Mircea
000255534 700__ $$aChemencedji, Inga
000255534 700__ $$aClipca, Adrian
000255534 700__ $$aDoruc, Serghei
000255534 700__ $$aGorincioi, Ghenadie
000255534 700__ $$aMura, Sergiu
000255534 700__ $$aPirtac, Maria
000255534 700__ $$aStancul, Irina
000255534 700__ $$aTcaciuc, Diana
000255534 700__ $$aAlbert, Monique
000255534 700__ $$aAlexopoulou, Iakovina
000255534 700__ $$aArnaout, Angel
000255534 700__ $$aBartlett, John
000255534 700__ $$aEngel, Jay
000255534 700__ $$aGilbert, Sebastien
000255534 700__ $$aParfitt, Jeremy
000255534 700__ $$aSekhon, Harman
000255534 700__ $$aThomas, George
000255534 700__ $$aRassl, Doris M.
000255534 700__ $$aRintoul, Robert C.
000255534 700__ $$aBifulco, Carlo
000255534 700__ $$aTamakawa, Raina
000255534 700__ $$aUrba, Walter
000255534 700__ $$aHayward, Nicholas
000255534 700__ $$aTimmers, Henri
000255534 700__ $$aAntenucci, Anna
000255534 700__ $$aFacciolo, Francesco
000255534 700__ $$aGrazi, Gianluca
000255534 700__ $$aMarino, Mirella
000255534 700__ $$aMerola, Roberta
000255534 700__ $$ade Krijger, Ronald
000255534 700__ $$aGimenez-Roqueplo, Anne-Paule
000255534 700__ $$aPiché, Alain
000255534 700__ $$aChevalier, Simone
000255534 700__ $$aMcKercher, Ginette
000255534 700__ $$aBirsoy, Kivanc
000255534 700__ $$aBarnett, Gene
000255534 700__ $$aBrewer, Cathy
000255534 700__ $$aFarver, Carol
000255534 700__ $$aNaska, Theresa
000255534 700__ $$aPennell, Nathan A.
000255534 700__ $$aRaymond, Daniel
000255534 700__ $$aSchilero, Cathy
000255534 700__ $$aSmolenski, Kathy
000255534 700__ $$aWilliams, Felicia
000255534 700__ $$aMorrison, Carl
000255534 700__ $$aBorgia, Jeffrey A.
000255534 700__ $$aLiptay, Michael J.
000255534 700__ $$aPool, Mark
000255534 700__ $$aSeder, Christopher W.
000255534 700__ $$aJunker, Kerstin
000255534 700__ $$aDinkin, Mikhail
000255534 700__ $$aManikhas, George
000255534 700__ $$aAlvaro, Domenico
000255534 700__ $$aBragazzi, Maria Consiglia
000255534 700__ $$aCardinale, Vincenzo
000255534 700__ $$aCarpino, Guido
000255534 700__ $$aGaudio, Eugenio
000255534 700__ $$aChesla, David
000255534 700__ $$aCottingham, Sandra
000255534 700__ $$aDubina, Michael
000255534 700__ $$aMoiseenko, Fedor
000255534 700__ $$aDhanasekaran, Renumathy
000255534 700__ $$aBecker, Karl-Friedrich
000255534 700__ $$aJanssen, Klaus-Peter
000255534 700__ $$aSlotta-Huspenina, Julia
000255534 700__ $$aAbdel-Rahman, Mohamed H.
000255534 700__ $$aAziz, Dina
000255534 700__ $$aBell, Sue
000255534 700__ $$aCebulla, Colleen M.
000255534 700__ $$aDavis, Amy
000255534 700__ $$aDuell, Rebecca
000255534 700__ $$aElder, J. Bradley
000255534 700__ $$aHilty, Joe
000255534 700__ $$aKumar, Bahavna
000255534 700__ $$aLang, James
000255534 700__ $$aLehman, Norman L.
000255534 700__ $$aMandt, Randy
000255534 700__ $$aNguyen, Phuong
000255534 700__ $$aPilarski, Robert
000255534 700__ $$aRai, Karan
000255534 700__ $$aSchoenfield, Lynn
000255534 700__ $$aSenecal, Kelly
000255534 700__ $$aWakely, Paul
000255534 700__ $$aHansen, Paul
000255534 700__ $$aLechan, Ronald
000255534 700__ $$aPowers, James
000255534 700__ $$aTischler, Arthur
000255534 700__ $$aGrizzle, William E.
000255534 700__ $$aSexton, Katherine C.
000255534 700__ $$aKastl, Alison
000255534 700__ $$aHenderson, Joel
000255534 700__ $$aPorten, Sima
000255534 700__ $$aWaldmann, Jens
000255534 700__ $$aFassnacht, Martin
000255534 700__ $$aAsa, Sylvia L.
000255534 700__ $$aSchadendorf, Dirk
000255534 700__ $$aCouce, Marta
000255534 700__ $$aGraefen, Markus
000255534 700__ $$aHuland, Hartwig
000255534 700__ $$aSauter, Guido
000255534 700__ $$aSchlomm, Thorsten
000255534 700__ $$aSimon, Ronald
000255534 700__ $$aTennstedt, Pierre
000255534 700__ $$aOlabode, Oluwole
000255534 700__ $$aNelson, Mark
000255534 700__ $$aBathe, Oliver
000255534 700__ $$aCarroll, Peter R.
000255534 700__ $$aChan, June M.
000255534 700__ $$aDisaia, Philip
000255534 700__ $$aGlenn, Pat
000255534 700__ $$aKelley, Robin K.
000255534 700__ $$aLanden, Charles N.
000255534 700__ $$aPhillips, Joanna
000255534 700__ $$aPrados, Michael
000255534 700__ $$aSimko, Jeffry
000255534 700__ $$aSmith-McCune, Karen
000255534 700__ $$aVandenBerg, Scott
000255534 700__ $$aRoggin, Kevin
000255534 700__ $$aFehrenbach, Ashley
000255534 700__ $$aKendler, Ady
000255534 700__ $$aSifri, Suzanne
000255534 700__ $$aSteele, Ruth
000255534 700__ $$aJimeno, Antonio
000255534 700__ $$aCarey, Francis
000255534 700__ $$aForgie, Ian
000255534 700__ $$aMannelli, Massimo
000255534 700__ $$aCarney, Michael
000255534 700__ $$aHernandez, Brenda
000255534 700__ $$aCampos, Benito
000255534 700__ $$aHerold-Mende, Christel
000255534 700__ $$aJungk, Christin
000255534 700__ $$aUnterberg, Andreas
000255534 700__ $$avon Deimling, Andreas
000255534 700__ $$aBossler, Aaron
000255534 700__ $$aGalbraith, Joseph
000255534 700__ $$aJacobus, Laura
000255534 700__ $$aKnudson, Michael
000255534 700__ $$aKnutson, Tina
000255534 700__ $$aMa, Deqin
000255534 700__ $$aMilhem, Mohammed
000255534 700__ $$aSigmund, Rita
000255534 700__ $$aMadan, Rashna
000255534 700__ $$aRosenthal, Howard G.
000255534 700__ $$aAdebamowo, Clement
000255534 700__ $$aAdebamowo, Sally N.
000255534 700__ $$aBoussioutas, Alex
000255534 700__ $$aBeer, David
000255534 700__ $$aGiordano, Thomas
000255534 700__ $$aMes-Masson, Anne-Marie
000255534 700__ $$aSaad, Fred
000255534 700__ $$aBocklage, Therese
000255534 700__ $$aLandrum, Lisa
000255534 700__ $$aMannel, Robert
000255534 700__ $$aMoore, Kathleen
000255534 700__ $$aMoxley, Katherine
000255534 700__ $$aPostier, Russel
000255534 700__ $$aWalker, Joan
000255534 700__ $$aZuna, Rosemary
000255534 700__ $$aFeldman, Michael
000255534 700__ $$aValdivieso, Federico
000255534 700__ $$aDhir, Rajiv
000255534 700__ $$aLuketich, James
000255534 700__ $$aPinero, Edna M. Mora
000255534 700__ $$aQuintero-Aguilo, Mario
000255534 700__ $$aCarlotti, Carlos Gilberto
000255534 700__ $$aDos Santos, Jose Sebastião
000255534 700__ $$aKemp, Rafael
000255534 700__ $$aSankarankuty, Ajith
000255534 700__ $$aTirapelli, Daniela
000255534 700__ $$aCatto, James
000255534 700__ $$aAgnew, Kathy
000255534 700__ $$aSwisher, Elizabeth
000255534 700__ $$aCreaney, Jenette
000255534 700__ $$aRobinson, Bruce
000255534 700__ $$aShelley, Carl Simon
000255534 700__ $$aGodwin, Eryn M.
000255534 700__ $$aKendall, Sara
000255534 700__ $$aShipman, Cassaundra
000255534 700__ $$aBradford, Carol
000255534 700__ $$aCarey, Thomas
000255534 700__ $$aHaddad, Andrea
000255534 700__ $$aMoyer, Jeffey
000255534 700__ $$aPeterson, Lisa
000255534 700__ $$aPrince, Mark
000255534 700__ $$aRozek, Laura
000255534 700__ $$aWolf, Gregory
000255534 700__ $$aBowman, Rayleen
000255534 700__ $$aFong, Kwun M.
000255534 700__ $$aYang, Ian
000255534 700__ $$aKorst, Robert
000255534 700__ $$aRathmell, W. Kimryn
000255534 700__ $$aFantacone-Campbell, J. Leigh
000255534 700__ $$aHooke, Jeffrey A.
000255534 700__ $$aKovatich, Albert J.
000255534 700__ $$aShriver, Craig D.
000255534 700__ $$aDiPersio, John
000255534 700__ $$aDrake, Bettina
000255534 700__ $$aGovindan, Ramaswamy
000255534 700__ $$aHeath, Sharon
000255534 700__ $$aLey, Timothy
000255534 700__ $$aVan Tine, Brian
000255534 700__ $$aWestervelt, Peter
000255534 700__ $$aRubin, Mark A.
000255534 700__ $$aLee, Jung Il
000255534 700__ $$aAredes, Natália D.
000255534 700__ $$aMariamidze, Armaz
000255534 773__ $$q338-354.e15$$k2$$j173$$tCell
000255534 8560_ $$fjoerg.huelsken@epfl.ch
000255534 8564_ $$uhttps://infoscience.epfl.ch/record/255534/files/final.pdf$$zFinal$$s9427158
000255534 909C0 $$xU11259$$pUPHUELSKEN$$mjoerg.huelsken@epfl.ch$$0252084
000255534 909CO $$qGLOBAL_SET$$pSV$$particle$$ooai:infoscience.epfl.ch:255534
000255534 960__ $$ajoerg.huelsken@epfl.ch
000255534 961__ $$apierre.devaud@epfl.ch
000255534 973__ $$aEPFL$$sPUBLISHED$$rREVIEWED
000255534 980__ $$aARTICLE
000255534 981__ $$aoverwrite