Consensus guidelines for the use and interpretation of angiogenesis assays
Nowak-Sliwinska, Patrycja; Alitalo, Kari; Allen, Elizabeth; Anisimov, Andrey; Aplin, Alfred C.; Auerbach, Robert; Augustin, Hellmut G.; Bates, David O.; van Beijnum, Judy R.; Bender, R. Hugh F.; Bergers, Gabriele; Bikfalvi, Andreas; Bischoff, Joyce; Böck, Barbara C.; Brooks, Peter C.; Bussolino, Federico; Cakir, Bertan; Carmeliet, Peter; Castranova, Daniel; Cimpean, Anca M.; Cleaver, Ondine; Coukos, George; Davis, George E.; De Palma, Michele; Dimberg, Anna; Dings, Ruud P. M.; Djonov, Valentin; Dudley, Andrew C.; Dufton, Neil P.; Fendt, Sarah-Maria; Ferrara, Napoleone; Fruttiger, Marcus; Fukumura, Dai; Ghesquière, Bart; Gong, Yan; Griffin, Robert J.; Harris, Adrian L.; Hughes, Christopher C. W.; Hultgren, Nan W.; Iruela-Arispe, M. Luisa; Irving, Melita; Jain, Rakesh K.; Kalluri, Raghu; Kalucka, Joanna; Kerbel, Robert S.; Kitajewski, Jan; Klaassen, Ingeborg; Kleinmann, Hynda K.; Koolwijk, Pieter; Kuczynski, Elisabeth; Kwak, Brenda R.; Marien, Koen; Melero-Martin, Juan M.; Munn, Lance L.; Nicosia, Roberto F.; Noel, Agnes; Nurro, Jussi; Olsson, Anna-Karin; Petrova, Tatiana V.; Pietras, Kristian; Pili, Roberto; Pollard, Jeffrey W.; Post, Mark J.; Quax, Paul H. A.; Rabinovich, Gabriel A.; Raica, Marius; Randi, Anna M.; Ribatti, Domenico; Ruegg, Curzio; Schlingemann, Reinier O.; Schulte-Merker, Stefan; Smith, Lois E. H.; Song, Jonathan W.; Stacker, Steven A.; Stalin, Jimmy; Stratman, Amber N.; Van de Velde, Maureen; van Hinsbergh, Victor W. M.; Vermeulen, Peter B.; Waltenberger, Johannes; Weinstein, Brant M.; Xin, Hong; Yetkin-Arik, Bahar; Yla-Herttuala, Seppo; Yoder, Mervin C.; Griffioen, Arjan W.
2018
Abstract
The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions. Angiogenesis undergoes multiple discrete steps that can be individually evaluated and quantified by a large number of bioassays. These independent assessments hold advantages but also have limitations. This article describes in vivo, ex vivo, and in vitro bioassays that are available for the evaluation of angiogenesis and highlights critical aspects that are relevant for their execution and proper interpretation. As such, this collaborative work is the first edition of consensus guidelines on angiogenesis bioassays to serve for current and future reference.
Details
Title
Consensus guidelines for the use and interpretation of angiogenesis assays
Author(s)
Nowak-Sliwinska, Patrycja ; Alitalo, Kari ; Allen, Elizabeth ; Anisimov, Andrey ; Aplin, Alfred C. ; Auerbach, Robert ; Augustin, Hellmut G. ; Bates, David O. ; van Beijnum, Judy R. ; Bender, R. Hugh F. ; Bergers, Gabriele ; Bikfalvi, Andreas ; Bischoff, Joyce ; Böck, Barbara C. ; Brooks, Peter C. ; Bussolino, Federico ; Cakir, Bertan ; Carmeliet, Peter ; Castranova, Daniel ; Cimpean, Anca M. ; Cleaver, Ondine ; Coukos, George ; Davis, George E. ; De Palma, Michele ; Dimberg, Anna ; Dings, Ruud P. M. ; Djonov, Valentin ; Dudley, Andrew C. ; Dufton, Neil P. ; Fendt, Sarah-Maria ; Ferrara, Napoleone ; Fruttiger, Marcus ; Fukumura, Dai ; Ghesquière, Bart ; Gong, Yan ; Griffin, Robert J. ; Harris, Adrian L. ; Hughes, Christopher C. W. ; Hultgren, Nan W. ; Iruela-Arispe, M. Luisa ; Irving, Melita ; Jain, Rakesh K. ; Kalluri, Raghu ; Kalucka, Joanna ; Kerbel, Robert S. ; Kitajewski, Jan ; Klaassen, Ingeborg ; Kleinmann, Hynda K. ; Koolwijk, Pieter ; Kuczynski, Elisabeth ; Kwak, Brenda R. ; Marien, Koen ; Melero-Martin, Juan M. ; Munn, Lance L. ; Nicosia, Roberto F. ; Noel, Agnes ; Nurro, Jussi ; Olsson, Anna-Karin ; Petrova, Tatiana V. ; Pietras, Kristian ; Pili, Roberto ; Pollard, Jeffrey W. ; Post, Mark J. ; Quax, Paul H. A. ; Rabinovich, Gabriel A. ; Raica, Marius ; Randi, Anna M. ; Ribatti, Domenico ; Ruegg, Curzio ; Schlingemann, Reinier O. ; Schulte-Merker, Stefan ; Smith, Lois E. H. ; Song, Jonathan W. ; Stacker, Steven A. ; Stalin, Jimmy ; Stratman, Amber N. ; Van de Velde, Maureen ; van Hinsbergh, Victor W. M. ; Vermeulen, Peter B. ; Waltenberger, Johannes ; Weinstein, Brant M. ; Xin, Hong ; Yetkin-Arik, Bahar ; Yla-Herttuala, Seppo ; Yoder, Mervin C. ; Griffioen, Arjan W.
Published in
Angiogenesis
Volume
21
Pages
425–532
Date
2018-05-15
Other identifier(s)
DOI: https://doi.org/10.1007/s10456-018-9613-x
Laboratories
UPDEPALMA
Record Appears in
Scientific production and competences > SV - School of Life Sciences > ISREC - Swiss Institute for Experimental Cancer Research > UPDEPALMA - Prof. De Palma Group
Peer-reviewed publications
Work produced at EPFL
Published
Reviews
Peer-reviewed publications
Work produced at EPFL
Published
Reviews
Record creation date
2018-06-01