A computational fluid-structure interaction analysis of coronary Y-grafts

Coronary artery disease is one of the leading causes of death worldwide. The stenotic coronary vessels are generally treated with coronary artery bypass grafts (CABGs), which can be either arterial (internal mammary artery, radial artery) or venous (saphenous vein). However, the different mechanical properties of the graft can influence the outcome of the procedure in terms of risk of restenosis and subsequent graft failure. In this paper, we perform a computational fluid-structure interaction (FSI) analysis of patient specific multiple CABGs (Y-grafts) with the aim of better understanding the influence of the choice of bypass (arterial vs venous) on the risk of graft failure. Our results show that the use of a venous bypass results in a more disturbed flow field at the anastomosis and in higher stresses in the vessel wall with respect to the arterial one. This could explain the better long-term patency of the arterial bypasses experienced in the clinical practice. (C) 2017 IPEM. Published by Elsevier Ltd. All rights reserved.


Published in:
Medical Engineering & Physics, 47, 117-127
Year:
2017
Publisher:
Oxford, Elsevier Sci Ltd
ISSN:
1350-4533
Keywords:
Laboratories:




 Record created 2017-10-09, last modified 2018-09-13


Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)