000231294 001__ 231294
000231294 005__ 20180317092339.0
000231294 013__ $$aWO2017158190$$bWO$$cA1$$d20170921
000231294 02470 $$2EPO Family ID$$a55628769
000231294 02470 $$2TTO$$a6.1502
000231294 037__ $$aPATENT
000231294 245__ $$aEnhancers of notch signaling and their use in the treatment of cancers and malignancies medicable by upregulation of notch
000231294 260__ $$c2017
000231294 269__ $$a2017
000231294 336__ $$aPatents
000231294 520__ $$aThe present invention relates to the use for enhancing Notch signaling in an individual, of a compound showing the general formula (I) and/or a pharmaceutically acceptable salt or ester thereof, for the treatment of a disease selected from the group of dermatological disorders including atopic dermatitis, psoriasis, immune related disorders, cancer, squamous cell carcinoma, cutaneous and lung squamous cell carcinoma, head and neck cancer, non-melanoma skin cancer, basal cell carcinoma and actinic keratosis, neuroendocrine tumors, neuroendocrine small cell carcinoma and carcinoid tumors, thyroid carcinomas, muscular disorders muscular dystrophy and impaired regeneration capacity after injury; use in immunotherapy for cancer.
000231294 700__ $$aReinmueller, Viktoria
000231294 700__ $$aZhu, Jieping
000231294 909C0 $$0252085$$pTTO$$xU10021
000231294 937__ $$aEPFL-PATENT-231294
000231294 973__ $$aEPFL
000231294 980__ $$aPATENT