Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors?
Bergmann, Timothy J.; Fumagalli, Fiorenza; Loi, Marisa; Molinari, Maurizio
2017

Abstract

Amplification of the candidate oncogene TLOC1/SEC62 in tumors correlates with reduced patient survival. The recently reported role of SEC62 as an autophagy receptor that controls endoplasmic reticulum (ER) size and function might open new scenarios for understanding the phenotypes and treat SEC62high tumors, which are characterized by high ER stress tolerance.

Details

Title Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors?
Author(s) Bergmann, Timothy J. ; Fumagalli, Fiorenza ; Loi, Marisa ; Molinari, Maurizio
Published in Molecular & Cellular Oncology
Pagination 3
Volume 4
Issue 2
Pages e1264351
Date 2017
Publisher Philadelphia, Taylor & Francis Inc
ISSN 2372-3556
Keywords
DOI https://doi.org/10.1080/23723556.2016.1264351
Other identifier(s) View record in Web of Science
Laboratories GHI
Record Appears in Scientific production and competences > SV - School of Life Sciences > GHI - Global Health Institute > UNATTRIBUTED-GHI - GHI - Unattributed publications
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date 2017-09-05