PHOTOELECTRIC NEURAL INTERFACE COMBINING WIRE-BONDING mu LEDS WITH IRIDIUM OXIDE MICROELECTRODES FOR OPTOGENETICS

This paper reports the design, fabrication, electrical and thermal characterization, as well as attachment and stability of a flexible photoelectric neural interface (PENI). Upon the wire-bonding technology, three micro LED (mu LED) chips are well-connected to the polyimide substrate as an array, with their luminous surfaces over against the holes. Meanwhile, a Parylene-C-based array with four microelectrodes (200 mu m in diameter) modified by sputtering iridium oxide film is fabricated to record micro electrocorticography (mu ECoG) signals. Then, the back-to-back assembly is utilized to allow blue light through the aligned holes on both arrays with almost no attenuation. As an optogenetics tool, the PENI can be attached on the cortical surface of a mouse expressing ChR2 to realize synchronized light modulating and neural signal recording.


Published in:
30Th Ieee International Conference On Micro Electro Mechanical Systems (Mems 2017), 538-541
Presented at:
30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Las Vegas, NV, JAN 22-26, 2017
Year:
2017
Publisher:
New York, Ieee
ISSN:
1084-6999
ISBN:
978-1-5090-5078-9
Laboratories:




 Record created 2017-07-10, last modified 2018-03-17


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