Polypeptide inhibitors of urokinase type plasminogen activator
Heinis, Christian; Angelini, Alessandro; Winter, Greg
2013

Abstract

A conjugate which is capable of specific binding to and inhibition of urokinase-type plasminigen activator (UPA) comprising a polypeptide molecule and a scaffold molecule, wherein said polypeptide molecule is attached to said scaffold molecule by at least three covalent bonds and wherein the inhibition constant (Ki) for said inhibitor is less than 500nM.

Details

Title Polypeptide inhibitors of urokinase type plasminogen activator
Author(s) Heinis, Christian ; Angelini, Alessandro ; Winter, Greg
Date 2013
Keywords
Note Alternative title(s) : (de) Polypeptide inhibitoren von urokinase-typ plasminogen aktivator (fr) Inhibiteurs polypeptidiques de l'activateur du plasminogène de type urokinase
Other identifier(s) EPO Family ID: 42984435
Patent number(s) EP2420255 (A3)
EP2420255 (A2)
GB201013980 (D0)
Laboratories LPPT
Record Appears in Scientific production and competences > SB - School of Basic Sciences > ISIC - Institute of Chemical Sciences and Engineering > LPPT - Laboratory of Therapeutic Proteins and Peptides
Work produced at EPFL
Patents
Record creation date 2017-06-13

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