000227727 001__ 227727
000227727 005__ 20181203024645.0
000227727 0247_ $$2doi$$a10.1242/dev.150201
000227727 022__ $$a0950-1991
000227727 02470 $$2ISI$$a000396224900002
000227727 037__ $$aARTICLE
000227727 245__ $$aThe hope and the hype of organoid research
000227727 260__ $$aCambridge$$bCompany of Biologists$$c2017
000227727 269__ $$a2017
000227727 300__ $$a4
000227727 336__ $$aJournal Articles
000227727 520__ $$aThe recent increase in organoid research has been met with great enthusiasm, as well as expectation, from the scientific community and the public alike. There is no doubt that this technology opens up a world of possibilities for scientific discovery in developmental biology as well as in translational research, but whether organoids can truly live up to this challenge is, for some, still an open question. In this Spotlight article, Meritxell Huch and Juergen Knoblich begin by discussing the exciting promise of organoid technology and give concrete examples of how this promise is starting to be realised. In the second part, Matthias Lutolf and Alfonso Martinez-Arias offer a careful and considered view of the state of the organoid field and its current limitations, and lay out the approach they feel is necessary to maximise the potential of organoid technology.
000227727 6531_ $$aDisease modelling
000227727 6531_ $$aOrganoids
000227727 6531_ $$aStem cells
000227727 6531_ $$aTherapies
000227727 700__ $$aHuch, Meritxell$$uUniv Cambridge, Wellcome Trust, Canc Res UK Gurdon Inst, Henry Wellcome Bldg Canc & Dev Biol,Tennis Court, Cambridge CB2 1QN, England
000227727 700__ $$aKnoblich, Juergen A.$$uAustrian Acad Sci, IMBA, Inst Mol Biotechnol, A-1030 Vienna, Austria
000227727 700__ $$0244264$$aLutolf, Matthias P.$$g106911$$uEcole Polytech Fed Lausanne, Sch Engn, CH-1015 Lausanne, Switzerland
000227727 700__ $$aMartinez-Arias, Alfonso
000227727 773__ $$j144$$k6$$q938-941$$tDevelopment
000227727 909C0 $$0252143$$pUPLUT$$xU11736
000227727 909CO $$ooai:infoscience.tind.io:227727$$pSV$$particle
000227727 917Z8 $$x184295
000227727 937__ $$aEPFL-ARTICLE-227727
000227727 973__ $$aEPFL$$rREVIEWED$$sPUBLISHED
000227727 980__ $$aARTICLE