Chain-Shattering Polymeric Therapeutics with On-Demand Drug-Release Capability

Trigger happy: Trigger-responsive chain-shattering polymeric therapeutics (CSPTs) were prepared by condensation polymerization of a UV- or hydrogen peroxide-responsive domain and a drug as co-monomers. Drug release can be started and stopped by starting and stopping the trigger treatment. Chemotherapeutic-containing CSPTs showed trigger-responsive in vitro and in vivo antitumor efficacy.


Published in:
Angewandte Chemie International Edition, 52, 25, 6435-6439
Year:
2013
Publisher:
Wiley-Blackwell
ISSN:
1433-7851
Laboratories:




 Record created 2016-08-15, last modified 2018-01-28


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