Osmolarity: A hidden factor in Nanotoxicology

In the field of drug delivery, long circulating nanocarriers in the blood have many advantages such as targeted drug delivery and sustained release. Based on our current knowledge, evaluation of the effect of long circulating nanocarriers in the blood stream on osmolarity of plasma has not been reported before. In this study, osmotic pressure developed by some commercially available nanocarriers was estimated based on Van't Hoff equation. It is noteworthy that theoretically, nanocarriers do not have any significant effect on osmolarity of plasma. However, it is worth being evaluated experimentally in order to be taken into account in future studies.


Published in:
Daru-Journal Of Pharmaceutical Sciences, 24, 9
Year:
2016
Publisher:
London, Biomed Central Ltd
ISSN:
2008-2231
Keywords:
Laboratories:




 Record created 2016-07-19, last modified 2018-09-13


Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)