An Integrated Platform for Differential Electrochemical and ISFET Sensing

A fully-integrated differential biosensing platform on CMOS is presented for miniaturized enzyme-based electrochemical sensing. It enables sensor background current elimination and consists of a differential sensor array and a <i>differential readout IC</i> (DiRIC). The sensor array includes a four-electrode sensor for amperometric electrochemical sensing, as well as a differential ISFET-based pH sensor to calibrate the biosensors. The ISFET is biased in weak inversion and co-designed with DiRIC to enable pH measurements from 1 to 14 with resolution of 0.1 pH. DiRIC enables differential current measurement in the range of ±100 μA with more than 120dB dynamic range.


Published in:
Proceedings of the IEEE International Symposium on Circuits and Systems (ISCAS), 2875-2878
Presented at:
IEEE International Symposium on Circuits and Systems (ISCAS), Montreal, Canada, May 22-25, 2016
Year:
2016
Publisher:
New York, IEEE
ISBN:
978-1-4799-5341-7
Keywords:
Laboratories:




 Record created 2016-06-14, last modified 2018-03-17

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