Thiazolium carbene catalysts for the fixation of CO2 onto amines

The catalytic N-formylation and N-methylation of amines using CO2 as the carbon source represents a facile and sustainable approach for the synthesis of pharmaceuticals and natural products. Herein, we describe highly effective and inexpensive thiazolium carbene-based catalysts derived from vitamin B1 for the N-formylation and N-methylation of amines, using polymethylhydrosiloxane (PMHS) as a reducing agent, which operate under ambient conditions.


Published in:
Chemical Communications, 52, 12, 2497-2500
Year:
2016
Publisher:
Cambridge, Royal Soc Chemistry
ISSN:
1359-7345
Laboratories:




 Record created 2016-04-01, last modified 2018-03-17


Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)